Lista prac opublikowanych przez pracowników Pracowni Genetyki Nowotworów w uznanych czasopismach naukowych o zasiegu międzynarodowym, od roku 2000

Papers published in the internationally recognized scientific journals by the staff of Laboratory of Tumour Genetics from 2000 year

Harlid S, Ivarsson MI, Butt S, Grzybowska E , Eyfjörd JE, Lenner P, Försti A, Hemminki K, Manjer J, Dillner J, Carlson J. Combined effect of low-penetrant SNPs on breast cancer risk. Br J Cancer 2011 Nov 1. doi: 10.1038/bjc.2011.461. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/22045194

Varadi V, Bevier M, Grzybowska E , Johansson R, Enquist-Olsson K, Henriksson R, Butkiewicz D, Pamula-Pilat J, Tecza K, Hemminki K, Lenner P, Försti A. Genetic variation in ALCAM and other chromosomal instability genes in breast cancer survival. Breast Cancer Res Treat . 2011 Sep 21. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/21935604

Shi H, Bevier M, Johansson R, Grzybowska E , Chen B, Eyfjörd JE, Hamann U, Manjer J, Enquist K, Henriksson R, Carlson J, Brandt A, Lascorz J, Butkiewicz D, Pamula-Pilat J, Tecza K , Herms S, Hoffmann P, Hemminki K, Lenner P, Försti A. Single nucleotide polymorphisms in the 20q13 amplicon genes in relation to breast cancer risk and clinical outcome. Breast Cancer Res Treat . 2011 Dec;130(3):905-16. Epub 2011 Jun 1.

http://www.ncbi.nlm.nih.gov/pubmed/21630024

Brozek I, Cybulska C, Ratajska M, Piatkowska M, Kluska A, Balabas A, Dabrowska M, Nowakowska D, Niwinska A, Pamula-Pilat J, Tecza K , Pekala W, Rembowska J, Nowicka K, Mosor M, Januszkiewicz-Lewandowska D, Rachtan J, Grzybowska E , Nowak J, Steffen J, Limon J. Prevalence of the most frequent BRCA1 mutations in Polish population. J Appl Genet . 2011 Aug;52(3):325-30. Epub 2011 Apr 19.

http://www.ncbi.nlm.nih.gov/pubmed/21503673

Free PMC Article http://www.ncbi.nlm.nih.gov/pubmed/21503673

Varadi V, Bevier M, Grzybowska E , Johansson R, Enquist K, Henriksson R, Butkiewicz D, Pamula-Pilat J, Tecza K , Hemminki K, Lenner P, Försti A. Genetic variation in genes encoding for polymerase ? subunits associates with breast cancer risk, tumour characteristics and survival. Breast Cancer Res Treat . 2011 Aug;129(1):235-45. Epub 2011 Apr 1.

http://www.ncbi.nlm.nih.gov/pubmed/21455670

Harlid S, Ivarsson MI, Butt S, Hussain S, Grzybowska E , Eyfjörd JE, Lenner P, Försti A, Hemminki K, Manjer J, Dillner J, Carlson J. A candidate CpG SNP approach identifies a breast cancer associated ESR1-SNP. Int J Cancer . 2011 Oct 1;129(7):1689-98. doi: 10.1002/ijc.25786. Epub 2011 Mar 11.

http://www.ncbi.nlm.nih.gov/pubmed/21105050

Byrski T, Gronwald J, Huzarski T, Grzybowska E , Budryk M, Stawicka M, Mierzwa T, Szwiec M, Wisniowski R, Siolek M, Dent R, Lubinski J, Narod S. Pathologic complete response rates in young women with BRCA1-positive breast cancers after neoadjuvant chemotherapy. J Clin Oncol . 2010 Jan 20;28(3):375-9. Epub 2009 Dec 14.

http://www.ncbi.nlm.nih.gov/pubmed/20008645

Jitkaew S, Trebinska A, Grzybowska E , Carlsson G, Nordström A, Lehtiö J, Fröjmark AS, Dahl N, Fadeel B. N(alpha)-tosyl-L-phenylalanine chloromethyl ketone induces caspase-dependent apoptosis in transformed human B cell lines with transcriptional down-regulation of anti-apoptotic HS1-associated protein X-1. J Biol Chem . 2009 Oct 9;284(41):27827-37. Epub 2009 Aug 13.

http://www.ncbi.nlm.nih.gov/pubmed/19679660

Free PMC Article http://www.ncbi.nlm.nih.gov/pubmed/19679660

Fadeel B, Grzybowska E . HAX-1: a multifunctional protein with emerging roles in human disease. Biochim Biophys Acta . 2009 Oct;1790(10):1139-48. Epub 2009 Jun 12. Review.

http://www.ncbi.nlm.nih.gov/pubmed/19524642

Carlsson G, Elinder G, Malmgren H, Trebinska A, Grzybowska E , Dahl N, Nordenskjöld M, Fadeel B. Compound heterozygous HAX1 mutations in a Swedish patient with severe congenital neutropenia and no neurodevelopmental abnormalities. Pediatr Blood Cancer . 2009 Dec;53(6):1143-6.

http://www.ncbi.nlm.nih.gov/pubmed/19499579

Varadi V, Brendle A, Grzybowska E , Johansson R, Enquist K, Butkiewicz D, Pamula-Pilat J , Pekala W , Hemminki K, Lenner P, Försti A. A functional promoter polymorphism in the TERT gene does not affect inherited susceptibility to breast cancer. Cancer Genet Cytogenet . 2009 Apr 15;190(2):71-4.

http://www.ncbi.nlm.nih.gov/pubmed/19380022

Carlsson G, van't Hooft I, Melin M, Entesarian M, Laurencikas E, Nennesmo I, Trebińska A, Grzybowska E , Palmblad J, Dahl N, Nordenskjöld M, Fadeel B, Henter JI. Central nervous system involvement in severe congenital neutropenia: neurological and neuropsychological abnormalities associated with specific HAX1 mutations. J Intern Med . 2008 Oct;264(4):388-400. Epub 2008 May 29.

http://www.ncbi.nlm.nih.gov/pubmed/18513342

Byrski T, Gronwald J, Huzarski T, Grzybowska E , Budryk M, Stawicka M, Mierzwa T, Szwiec M, Wiśniowski R, Siolek M, Narod SA, Lubinski J; Polish Hereditary Breast Cancer Consortium. Response to neo-adjuvant chemotherapy in women with BRCA1-positive breast cancers. Breast Cancer Res Treat . 2008 Mar;108(2):289-96. Epub 2007 May 10.

http://www.ncbi.nlm.nih.gov/pubmed/17492376

Wagner K, Grzybowska E , Butkiewicz D, Pamula-Pilat J , Pekala W , Tecza K, Hemminki K, Försti A. High-throughput genotyping of a common deletion polymorphism disrupting the TRY6 gene and its association with breast cancer risk. BMC Genet . 2007 Jun 29;8:41.

http://www.ncbi.nlm.nih.gov/pubmed/17598925

Free PMC Article http://www.ncbi.nlm.nih.gov/pubmed/17598925

Försti A, Jin Q, Altieri A, Johansson R, Wagner K, Enquist K, Grzybowska E , Pamula J , Pekala W , Hallmans G, Lenner P, Hemminki K. Polymorphisms in the KDR and POSTN genes: association with breast cancer susceptibility and prognosis. Breast Cancer Res Treat . 2007 Jan;101(1):83-93. Epub 2006 Jun 29.

http://www.ncbi.nlm.nih.gov/pubmed/16807673

Debniak T, Scott RJ, Huzarski T, Byrski T, Masojć B, van de Wetering T, Serrano-Fernandez P, Górski B, Cybulski C, Gronwald J, Debniak B, Maleszka R, Kładny J, Bieniek A, Nagay L, Haus O, Grzybowska E , Wandzel P, Niepsuj S, Narod SA, Lubinski J. XPD common variants and their association with melanoma and breast cancer risk. Breast Cancer Res Treat . 2006 Jul;98(2):209-15. Epub 2006 May 10.

http://www.ncbi.nlm.nih.gov/pubmed/16685590

Wagner K, Hemminki K, Grzybowska E , Klaes R, Burwinkel B, Bugert P, Schmutzler RK, Wappenschmidt B, Butkiewicz D, Pamula J , Pekala W , Försti A. Polymorphisms in genes involved in GH1 release and their association with breast cancer risk. Carcinogenesis . 2006 Sep;27(9):1867-75. Epub 2006 Apr 10. http://www.ncbi.nlm.nih.gov/pubmed/16606630

Free Article http://carcin.oxfordjournals.org/content/27/9/1867.long

Lubiński J, Górski B, Huzarski T, Byrski T, Gronwald J, Serrano-Fernández P, Domagała W, Chosia M, Uciński M, Grzybowska E , Lange D, Maka B, Mackiewicz A, Karczewska A, Breborowicz J, Lamperska K, Stawicka M, Gozdecka-Grodecka S, Bebenek M, Sorokin D, Wojnar A, Haus O, Sir J, Mierzwa T, Niepsuj S, Gugała K, Góźdź S, Sygut J, Kozak-Klonowska B, Musiatowicz B, Posmyk M, Kordek R, Morawiec M, Zambrano O, Waśko B, Fudali L, Skret J, Surdyka D, Urbański K, Mituś J, Ryś J, Szwiec M, Rozmiarek A, Dziuba I, Wandzel P, Wiśniowski R, Szczylik C, Kozak A, Kozłowski W, Narod SA. BRCA1-positive breast cancers in young women from Poland . Breast Cancer Res Treat . 2006 Sep;99(1):71-6. Epub 2006 Mar 16. http://www.ncbi.nlm.nih.gov/pubmed/16541315

Dudaladava V, Jarzab M, Stobiecka E, Chmielik E, Simek K, Huzarski T, Lubiński J, Pamuła J , Pekala W , Grzybowska E , Lisowska K. Gene Expression Profiling in Hereditary, BRCA1-linked Breast Cancer: Preliminary Report. Hered Cancer Clin Pract . 2006 Jan 15;4(1):28-38. http://www.ncbi.nlm.nih.gov/pubmed/20223001

Pamuła J , Krześniak M, Zientek H, Pekala W , Rusin M, Grzybowska E . Functional Impact of Sequence Alterations Found in BRCA1 Promoter/5'UTR Region in Breast/Ovarian Cancer Families from Upper Silesia, Poland. Hered Cancer Clin Pract . 2006 Jan 15;4(1):20-4. http://www.ncbi.nlm.nih.gov/pubmed/20222999

Wagner K, Hemminki K, Grzybowska E , Bermejo JL, Butkiewicz D, Pamula J , Pekala W , Försti A. Polymorphisms in the growth hormone receptor: a case-control study in breast cancer. Int J Cancer . 2006 Jun 1;118(11):2903-6. http://www.ncbi.nlm.nih.gov/pubmed/16381017

Wagner K, Hemminki K, Israelsson E, Grzybowska E , Klaes R, Chen B, Butkiewicz D, Pamula J , Pekala W , Försti A. Association of polymorphisms and haplotypes in the human growth hormone 1 (GH1) gene with breast cancer. Endocr Relat Cancer . 2005 Dec;12(4):917-28. http://www.ncbi.nlm.nih.gov/pubmed/16322331

Free Article http://erc.endocrinology-journals.org/content/12/4/917.long

Wagner K, Hemminki K, Israelsson E, Grzybowska E , Söderberg M, Pamula J , Pekala W , Zientek H , Mielzynska D, Siwinska E, Försti A. Polymorphisms in the IGF-1 and IGFBP 3 promoter and the risk of breast cancer. Breast Cancer Res Treat . 2005 Jul;92(2):133-40. http://www.ncbi.nlm.nih.gov/pubmed/15986122

Wirtenberger M, Hemminki K, Försti A, Klaes R, Schmutzler RK, Grzybowska E , Bermejo JL, Wappenschmidt B, Bugert P, Butkiewicz D, Pamula J , Pekala W , Zientek H , Bartram CR, Burwinkel B. c-MYC Asn11Ser is associated with increased risk for familial breast cancer. Int J Cancer . 2005 Nov 20;117(4):638-42. http://www.ncbi.nlm.nih.gov/pubmed/15929079

Jin Q, Hemminki K, Enquist K, Lenner P, Grzybowska E , Klaes R, Henriksson R, Chen B, Pamula J , Pekala W , Zientek H , Rogozinska-Szczepka J, Utracka-Hutka B, Hallmans G, Försti A. Vascular endothelial growth factor polymorphisms in relation to breast cancer development and prognosis. Clin Cancer Res . 2005 May 15;11(10):3647-53. http://www.ncbi.nlm.nih.gov/pubmed/15897560

Free Article http://clincancerres.aacrjournals.org/content/11/10/3647.long

Debniak T, Górski B, Huzarski T, Byrski T, Cybulski C, Mackiewicz A, Gozdecka-Grodecka S, Gronwald J, Kowalska E, Haus O, Grzybowska E , Stawicka M, Swiec M, Urbański K, Niepsuj S, Waśko B, Góźdź S, Wandzel P, Szczylik C, Surdyka D, Rozmiarek A, Zambrano O, Posmyk M, Narod SA, Lubinski J. A common variant of CDKN2A (p16) predisposes to breast cancer. J Med Genet . 2005 Oct;42(10):763-5. Epub 2005 May 6.

http://www.ncbi.nlm.nih.gov/pubmed/15879498

Free PMC Article http://jmg.bmj.com/content/42/10/763.long

Burwinkel B, Wirtenberger M, Klaes R, Schmutzler RK, Grzybowska E , Försti A, Frank B, Bermejo JL, Bugert P, Wappenschmidt B, Butkiewicz D, Pamula J , Pekala W , Zientek H , Mielzynska D, Siwinska E, Bartram CR, Hemminki K. Association of NCOA3 polymorphisms with breast cancer risk. Clin Cancer Res . 2005 Mar 15;11(6):2169-74.

http://www.ncbi.nlm.nih.gov/pubmed/15788663

Free Article http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1735931/pdf/v042p00763.pdf

Wilkening S, Burwinkel B, Grzybowska E , Klaes R, Pamula J , Pekala W , Zientek H , Hemminki K, Försti A. Polyglutamine repeat length in the NCOA3 does not affect risk in familial breast cancer. Cancer Epidemiol Biomarkers Prev . 2005 Jan;14(1):291-2. No abstract available. http://www.ncbi.nlm.nih.gov/pubmed/15668512

Free Article http://cebp.aacrjournals.org/content/14/1/291.long

Rogozińska-Szczepka J, Utracka-Hutka B, Grzybowska E , Maka B, Nowicka E, Smok-Ragankiewicz A, Zientek H , Steffen J, Wojciechowska-Łacka A. BRCA1 and BRCA2 mutations as prognostic factors in bilateral breast cancer patients. Ann Oncol . 2004 Sep;15(9):1373-6.

http://www.ncbi.nlm.nih.gov/pubmed/15319244

Free Article http://annonc.oxfordjournals.org/content/15/9/1373.long

Wagner K, Hemminki K, Grzybowska E , Klaes R, Butkiewicz D, Pamula J, Pekala W, Zientek H, Mielzynska D, Siwinska E, Försti A. The insulin-like growth factor-1 pathway mediator genes: SHC1 Met300Val shows a protective effect in breast cancer. Carcinogenesis . 2004 Dec;25(12):2473-8. Epub 2004 Aug 12.

http://www.ncbi.nlm.nih.gov/pubmed/15308584

Free Article http://carcin.oxfordjournals.org/content/25/12/2473.long

Jin Q, Hemminki K, Grzybowska E , Klaes R, Söderberg M, Zientek H , Rogozinska-Szczepka J, Utracka-Hutka B, Pamula J , Pekala W , Försti A. Polymorphisms and haplotype structures in genes for transforming growth factor beta1 and its receptors in familial and unselected breast cancers. Int J Cancer . 2004 Oct 20;112(1):94-9.

http://www.ncbi.nlm.nih.gov/pubmed/15305380

Górski B, Jakubowska A, Huzarski T, Byrski T, Gronwald J, Grzybowska E , Mackiewicz A, Stawicka M, Bebenek M, Sorokin D, Fiszer-Maliszewska Ł, Haus O, Janiszewska H, Niepsuj S, Góźdź S, Zaremba L, Posmyk M, Płuzańska M, Kilar E, Czudowska D, Waśko B, Miturski R, Kowalczyk JR, Urbański K, Szwiec M, Koc J, Debniak B, Rozmiarek A, Debniak T, Cybulski C, Kowalska E, Tołoczko-Grabarek A, Zajaczek S, Menkiszak J, Medrek K, Masojć B, Mierzejewski M, Narod SA, Lubiński J. A high proportion of founder BRCA1 mutations in Polish breast cancer families. Int J Cancer . 2004 Jul 10;110(5):683-6.

http://www.ncbi.nlm.nih.gov/pubmed/15146557

Försti A, Angelini S, Festa F, Sanyal S, Zhang Z, Grzybowska E , Pamula J , Pekala W , Zientek H , Hemminki K, Kumar R. Single nucleotide polymorphisms in breast cancer. Oncol Rep . 2004 Apr;11(4):917-22.

http://www.ncbi.nlm.nih.gov/pubmed/15010895

Rusin M, Zientek H, Krześniak M, Małusecka E, Zborek A, Krzyzowska-Gruca S, Butkiewicz D, Vaitiekunaite R, Lisowska K, Grzybowska E , Krawczyk Z. Intronic polymorphism (1541-1542delGT) of the constitutive heat shock protein 70 gene has functional significance and shows evidence of association with lung cancer risk. Mol Carcinog . 2004 Mar;39(3):155-63.

http://www.ncbi.nlm.nih.gov/pubmed/14991745

Jin Q, Hemminki K, Grzybowska E , Klaes R, Söderberg M, Försti A. Re: Integrin beta3 Leu33Pro homozygosity and risk of cancer. J Natl Cancer Inst . 2004 Feb 4;96(3):234-5; author reply 235. No abstract available.

http://www.ncbi.nlm.nih.gov/pubmed/14759991

Free Article http://jnci.oxfordjournals.org/content/96/3/234.long

Menkiszak J, Gronwald J, Górski B, Jakubowska A, Huzarski T, Byrski T, Foszczyńska-Kłoda M, Haus O, Janiszewska H, Perkowska M, Brozek I, Grzybowska E , Zientek H , Góźdź S, Kozak-Klonowska B, Urbański K, Miturski R, Kowalczyk J, Pluzańska A, Niepsuj S, Koc J, Szwiec M, Drosik K, Mackiewicz A, Lamperska K, Strózyk E, Godlewski D, Stawicka M, Waśko B, Bebenek M, Rozmiarek A, Rzepka-Górska I, Narod SA, Lubiński J. Hereditary ovarian cancer in Poland. Int J Cancer . 2003 Oct 10;106(6):942-5.

http://www.ncbi.nlm.nih.gov/pubmed/12918074

Grzybowska E , Siemińska M, Zientek H , Kalinowska E, Michalska J, Utracka-Hutka B, Rogozińska-Szczepka J, Kaźmierczak-Maciejewska M. Germline mutations in the BRCA1 gene predisposing to breast and ovarian cancers in Upper Silesia population. Acta Biochim Pol . 2002;49(2):351-6.

http://www.ncbi.nlm.nih.gov/pubmed/12362976

Free Article http://www.actabp.pl/pdf/2_2002/351.pdf

Försti A, Jin Q, Grzybowska E , Söderberg M, Zientek H , Sieminska M, Rogozinska-Szczepka J, Chmielik E, Utracka-Hutka B, Hemminki K. Sex hormone-binding globulin polymorphisms in familial and sporadic breast cancer. Carcinogenesis . 2002 Aug;23(8):1315-20.

http://www.ncbi.nlm.nih.gov/pubmed/12151349

Free Article http://carcin.oxfordjournals.org/content/23/8/1315.long

Grzybowska E , Góra M, Plochocka D, Rytka J. Saccharomyces cerevisiae ferrochelatase forms a homodimer. Arch Biochem Biophys . 2002 Feb 15;398(2):170-8.

http://www.ncbi.nlm.nih.gov/pubmed/11831847

Grzybowska E , Butkiewicz D, Motykiewicz G, Chorazy M. The effect of the genetic polymorphisms of CYP1A1,CYP2D6, GSTM1 and GSTP1 on aromatic DNA adduct levels in the population of healthy women. Mutat Res . 2000 Sep 20;469(2):271-7.

http://www.ncbi.nlm.nih.gov/pubmed/10984688

Górski B, Byrski T, Huzarski T, Jakubowska A, Menkiszak J, Gronwald J, Pluzańska A, Bebenek M, Fischer-Maliszewska L, Grzybowska E , Narod SA, Lubiński J. Founder mutations in the BRCA1 gene in Polish families with breast-ovarian cancer. Am J Hum Genet . 2000 Jun;66(6):1963-8. Epub 2000 Apr 28.

http://www.ncbi.nlm.nih.gov/pubmed/10788334

Free PMC Article http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1378051/pdf/10788334.pdf

Butkiewicz D, Grzybowska E , Phillips DH, Hemminki K, Chorazy M. Polymorphisms of the GSTP1 and GSTM1 genes and PAH-DNA adducts in human mononuclear white blood cells. Environ Mol Mutagen. 2000;35(2):99-105.

http://www.ncbi.nlm.nih.gov/pubmed/10712743

Grzybowska E , Zientek H , Jasinska A, Rusin M, Kozlowski P, Sobczak K, Sikorska A, Kwiatkowska E, Gorniak L, Kalinowska E, Utracka-Hutka B, Wloch J, Chmielik E, Krzyzosiak WJ. High frequency of recurrent mutations in BRCA1 and BRCA2 genes in Polish families with breast and ovarian cancer. Hum Mutat . 2000 Dec;16(6):482-90.

http://www.ncbi.nlm.nih.gov/pubmed/11102977