Magdalena Olbryt, Ph.D. - research assistant

 

Magdalena Olbryt graduated in 2001 from the Faculty of Biology and Environmental Protection, University of Silesia in Katowice. As a participant of Socrates/Erasmus program she spent one year at the Aarhus University (Denmark) where she completed a molecular biology course and practice at the Laboratory of Gene Expression headed by Professor Jens Stougaard. Since 2001 she has worked at the Research Department of the Maria Skłodowska-Curie Memorial Cancer Center and Institute of Oncology in Gliwice. In 2010 she has defended her Ph.D thesis entitled “Gene expression priofile induced by hypoxia in B16-F10 murine melanoma cells” (supervisor: Professor Zdzisław Krawczyk; reviewers: Professor Janusz Siedlecki and Professor Ryszard Oliński). Currently, as a research assistant she has been involved in projects concerning various fields of cancer molecular biology including melanoma and hypoxia. She is the author or co-author of 11 original and review papers (IF approx. 49). She also participates in the National Program of Cancer Prevention by giving lectures on cancer biology and primary prevention.

 

 Publications:

Olbryt M, Rusin A, Fokt I, Habryka A, Tudrej P, Student S, Sochanik A, Zieliński R, Priebe W. (2017) Bis-anthracycline WP760 abrogates melanoma cell growth by transcription inhibition, p53 activation and IGF1R downregulation. Invest New Drugs. 2017 Apr 17. doi: 10.1007/s10637-017-0465-9. [Epub ahead of print]

Szafron LM, Balcerak A, Grzybowska EA, Pienkowska-Grela B, Podgorska A, Zub R, Olbryt M, Pamula-Pilat J, Lisowska KM, Grzybowska E, Rubel T, Dansonka-Mieszkowska A, Konopka B, Kulesza M, Lukasik M, Kupryjanczyk J. The putative oncogene, CRNDE, is a negative prognostic factor in ovarian cancer patients. Oncotarget. 2015 Nov 4. doi: 10.18632/oncotarget.6016

Pamuła- Piłat J., Rubel T., Rzepecka I.T., Olbryt M.,  Herok R., Dansonska-Mieszkowska A., Grzybowska E., Kupryjańczyk J. Gene expression profiles in three histologic types, clear-cell, endometrioid, serous ovarian carcinomas. Journal of Biological Regulators & Homeostatic Agents Vol. 28, no. 4, 659-674 (2014).

Lisowska KM, Olbryt M, Dudaladava V, Pamuła-Piłat J, Kujawa K, Grzybowska E, Jarząb M, Student S, Rzepecka IK, Jarząb B, Kupryjańczyk J. (2014): Gene expression analysis in ovarian cancer - faults and hints from DNA microarray study. Front Oncol. 2014 Jan 28;4:6. doi: 10.3389/fonc.2014.00006. eCollection 2014.
http://www.ncbi.nlm.nih.gov/pubmed/24478986

Kuś-Liśkiewicz M, Polańska J, Korfanty J, Olbryt M, Vydra, N, Toma A, Widłak, (2013):Impact of heat shock transcription factor 1 on global gene expression profiles in cells which induce either cytoprotective or pro-apoptotic response following hyperthermia, BMC Genomics; 14:456,

http://www.biomedcentral.com/1471-2164/14/456/abstract  

 

Magdalena Olbryt, (2013): Role of tumor microenvironment in the formation and progression of skin melanoma. Postepy Hig Med Dosw; 67 413-432; (article in Polish)

 Mazurek AM, Olbryt M. (2012): The influence of neuropilin-1 silencing on semaphorin 3A and 3C activity in B16(F10) murine melanoma cells. Neoplasma; 59: 43-51.

http://www.ncbi.nlm.nih.gov/pubmed/22082309

 Olbryt M, Habryka A, Tyszkiewicz T, Rusin A, Cichoń T, Jarząb M. Krawczyk Z (2011): Melanoma-associated genes, MXI1, FN1, and NME1, are hypoxia responsive in murine and human melanoma cells. Melanoma Res; 21: 417-25.

http://www.ncbi.nlm.nih.gov/pubmed/21912348

 Olbryt M, Jarząb M, Jazowiecka-Rakus A, Simek K, Szala S, Sochanik A (2006): Gene expression profile of B16(F10) murine melanoma cells exposed to hypoxic conditions in vitro. Gene Expression, 13: 91-203.

http://www.ncbi.nlm.nih.gov/pubmed/17193925

 Olbryt M, Szala S: Białkowe inhibitory angiogenezy w terapii nowotworów. Współczesna Onkologia, 9, 48-53, 2005

 Madsen E.B, Madsen L.H, Radutoiu S, Olbryt M, Rakwalska M, Szczyglowski K, Sato S, Kaneko T, Rabata S, Sandal N & Stougaard J (2003): A receptor kinase gene of the LysM type is involved in legume perception of rhizobial signals. Nature; 425: 637-640.

http://www.ncbi.nlm.nih.gov/pubmed/14534591

 Sandal N, Krusell L, Radutoiu S, Olbryt M, Pedrosa A, Stracke S, Sato S, Kato T. Tabata S, Parniske M, Bachmair A, Ketelsen T, Stougaard J (2002): A genetic linkage map of the model legume Lotus japonicus and strategies for fast mapping of new loci. Genetics; 161: 1673-1683.

http://www.ncbi.nlm.nih.gov/pubmed/12196410

  

Other scientific interests (recommended links /publications):

 - Melanoma

 „Melanoma Genetics Consortium”

http://www.genomel.org/,

 „The Wistar Institute Melanoma Research Center”

http://www.wistar.org/our-science/wistar-centers/melanoma-research-center,

 

„Melanoma Molecular Map Project”

http://www.mmmp.org/MMMP/import.mmmp?page=mol_bio.mmmp

 

- Cancer prevention

„Kodeks walki z rakiem”

http://www.kodekswalkizrakiem.pl/content/view/56/113/

 

„National Toxicology program”

http://ntp.niehs.nih.gov/

 

„Foods That Fight Cancer”- Preventing Cancer through Diet; Richard Beliveau, Denis Gingras

 

- Ethics in science, bio-ethics

 „Dobre obyczaje w nauce”

http://www.ken.pan.pl/images/stories/pliki/pdf/down.pdf

 

to be continued…


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