Ważniejsze prace naukowe pracowników Centrum Badań Translacyjnych i Biologii Molekularnej Nowotworów

2017

Pietrowska M, Diehl HC, Mrukwa G, Kalinowska-Herok M, Gawin M, Chekan M, Elm J, Drazek G, Krawczyk A, Lange D, Meyer HE, Polanska J, Henkel C, Widlak P (2017) Molecular profiles of thyroid cancer subtypes: Classification based on features of tissue revealed by mass spectrometry imaging. Biochim Biophys Acta. doi: 10.1016/j.bbapap.2016.10.006 [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/27760391

Roś-Mazurczyk M, Wojakowska A, Marczak Ł, Polański K, Pietrowska M, Jelonek K, Domińczyk I, Hajduk A, Rutkowski T, Składowski K, Widłak P (2017) Ionizing radiation affects profile of serum metabolites: increased level of 3-hydroxybutyric acid in serum of cancer patients treated with radiotherapy. Acta Biochim Pol. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/27815965

Szoltysek K, Walaszczyk A, Janus P, Kimmel M, Widlak P (2017) Irradiation with UV-C inhibits TNF-α-dependent activation of the NF-κB pathway in a mechanism potentially mediated by reactive oxygen species. Genes Cells. 22: 45-58.

https://www.ncbi.nlm.nih.gov/pubmed/27976481

Snietura M, Chelmecka-Wiktorczyk L, Pakulo S, Kopec A, Piglowski W, Drabik G, Kosowski B, Wyrobek L, Stanek-Widera A, Balwierz W (2017) Vertically transmitted HPV-dependent squamous cell carcinoma of the external auditory canal: Case report of a child. Strahlenther Onkol. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/27646207

Walaszczyk A, Pietrowska M, Wojakowska A, Abramowicz A, Chmura A, Masłyk B, Rodziewicz P, Polańska J, Behrendt K, Nowicka E, Tarnawski R, Widłak P (2017) Therapy-related changes in serum proteome patterns of early stage breast cancer patients with different outcome. Protein Pept Lett. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/27894246

 

2016

Abramowicz A, Widlak P, Pietrowska M (2016) Proteomic analysis of exosomal cargo: the challenge of high purity vesicle isolation. Mol Biosyst. 12: 1407-1419.

https://www.ncbi.nlm.nih.gov/pubmed/27030573

Czapla J, Matuszczak S, Wiśniewska E, Jarosz-Biej M, Smolarczyk R, Cichoń T, Głowala-Kosińska M, Śliwka J, Garbacz M, Szczypior M, Jaźwiec T, Langrzyk A, Zembala M, Szala S (2016) Human cardiac mesenchymal stromal cells with CD105+CD34- phenotype enhance the function of post-infarction heart in mice. PLoS One 11: e0158745.

https://www.ncbi.nlm.nih.gov/pubmed/27415778

Gadher SJ, Marczak Ł, Łuczak M, Stobiecki M, Widlak P, Kovarova H (2016) Proteomic landscape in Central and Eastern Europe: the 9th Central and Eastern European Proteomic Conference, Poznań, Poland. Expert Rev Proteomics 13, 5-7.

https://www.ncbi.nlm.nih.gov/pubmed/26558656

Huszno J, Budryk M, Kołosza Z, Tęcza K, Pamuła Piłat J, Nowara E, Grzybowska E (2016) A Comparison between CHEK2*1100delC/I157T Mutation Carrier and Noncarrier Breast Cancer Patients: A Clinicopathological Analysis. Oncology 90: 193-198.

https://www.ncbi.nlm.nih.gov/pubmed/26991782

Huzarski T, Byrski T, Gronwald J, Cybulski C, Oszurek O, Szwiec M, Gugała K, Stawicka M, Morawiec Z, Mierzwa T, Falco M, Janiszewska H, Kilar E, Marczyk E, Kozak-Klonowska B, Siołek M, Surdyka D, Wiśniowski R, Posmyk M, Domagała P, Sun P, Lubiński J, Narod SA; Polish Breast Cancer Consortium (2016) The impact of oophorectomy on survival after breast cancer in BRCA1-positive breast cancer patients. Breast Cancer Res Treat. 156: 371-378.

https://www.ncbi.nlm.nih.gov/pubmed/26983446

Jelonek K, Widlak P, Pietrowska M (2016) The Influence of Ionizing Radiation on Exosome Composition, Secretion and Intercellular Communication. Protein Pept Lett. 23: 656-663.

https://www.ncbi.nlm.nih.gov/pubmed/27117741

Jelonek K, Pietrowska M, Widłak P (2016) Główne zmiany proteomu i metabolomu surowicy obserwowane w krwi osób poddanych radioterapii dotyczą wskaźników stanu zapalnego i odpowiedzi immunologicznej odzwierciedlających systemową toksyczność promieniowania jonizującego. Oncology and Radiotherapy 3, 24-29.

http://onkologia.medicalproject.com.pl/download.php?idArt=904

Jonak K, Kurpas M, Szoltysek K, Janus P, Abramowicz A, Puszynski K (2016) A novel mathematical model of ATM/p53/NF- κB pathways points to the importance of the DDR switch-off mechanisms. BMC Syst Biol. 10:75, Erratum in: BMC Syst Biol. 10: 99.

https://www.ncbi.nlm.nih.gov/pubmed/27526774

Kamysz E, Smolarczyk R, Cichoń T, Jarosz-Biej M, Sikorska E, Sobocińska M, Jaśkiewicz M, Kamysz W (2016) Antitumor activity of opiorphin, sialorphin and their conjugates with a peptide klaklakklaklak. J Pept Sci. 22: 723-730.

https://www.ncbi.nlm.nih.gov/pubmed/27862720

Lisowska KM, Olbryt M, Student S, Kujawa KA, Cortez AJ, Simek K, Dansonka-Mieszkowska A, Rzepecka IK, Tudrej P, Kupryjańczyk J (2016) Unsupervised analysis reveals two molecular subgroups of serous ovarian cancer with distinct gene expression profiles and survival. J Cancer Res Clin Oncol. 142: 1239-1252.

https://www.ncbi.nlm.nih.gov/pubmed/27028324

Liśkiewicz AD, Kasprowska D, Wojakowska A, Polański K, Lewin-Kowalik J, Kotulska K, Jędrzejowska-Szypułka H (2016) Long-term high fat ketogenic diet promotes renal tumor growth in a rat model of tuberous sclerosis. Sci Rep. 6: 21807.

https://www.ncbi.nlm.nih.gov/pubmed/26892894

Mazurek AM, Rutkowski T, Fiszer-Kierzkowska A, Małusecka E, Składowski K (2016) Assessment of the total cfDNA and HPV16/18 detection in plasma samples of head and neck squamous cell carcinoma patients. Oral Oncol. 54: 36-41.

www.ncbi.nlm.nih.gov/pubmed/26786940

Pamuła-Piłat J, Tęcza K, Grzybowska E (2016) Profile molekularne raka piersi. Laboratorium 9-10/2016, 8-13.

http://yadda.icm.edu.pl/yadda/element/bwmeta1.element.baztech-12eb0f5b-db98-466e-a42f-773d2cf35811

Pentak D, Kozik V, Bąk A, Dybał P, Sochanik A, Jampilek J (2016) Methotrexate and Cytarabine-Loaded Nanocarriers for Multidrug Cancer Therapy. Spectroscopic Study. Molecules 21. pii: E1689.

https://www.ncbi.nlm.nih.gov/pubmed/27941655

Pietrowska M, Gawin M, Polańska J, Widłak P (2016) Tissue fixed with formalin and processed without paraffin embedding is suitable for imaging of both peptides and lipids by MALDI-IMS. Proteomics 16: 1670-1677.

https://www.ncbi.nlm.nih.gov/pubmed/27001204

Roś-Mazurczyk M, Jelonek K, Pietrowska M, Zagdański A, Suchwałko A, Jastrząb T, Polańska J, Chawińska E, Majewski W, Domińczyk I, Rutkowski T, Miszczyk L, Składowski K, Widłak P (2016): Radiotherapy-induced changes in serum lipid profile of patients with prostate or head and neck cancer. J J Rad Oncol. 3(2): 030.

http://radiationoncology.jacobspublishers.com/images/Rad_Onco/J_J_Rad_Oncol_3_2_030.pdf

Szymańska K, Pietrowska M, Kocurek J, Maresz K, Koreniuk A, Mrowiec-Białoń J, Widłak P, Magner E, Jarzębski A (2016) Low back-pressure hierarchically structured multichannel microfluidic bioreactors for rapid protein digestion - proof of concept. Chem Eng J  287:148-54.

http://dx.doi.org/10.1016/j.cej.2015.10.120

Tecza K, Pamula-Pilat J, Lanuszewska J, Grzybowska E (2016) Genetic polymorphisms and response to 5-fluorouracil, doxorubicin and cyclophosphamide chemotherapy in breast cancer patients. Oncotarget 7: 66790-66808.

https://www.ncbi.nlm.nih.gov/pubmed/27527855

Tóth E, Vékey K, Ozohanics O, Jekő A, Dominczyk I, Widlak P, Drahos L (2016) Changes of protein glycosylation in the course of radiotherapy. J Pharm Biomed Anal. 118: 380-386.

https://www.ncbi.nlm.nih.gov/pubmed/26609677

Waniczek D, Snietura M, Kopec A, Scieglinska D, Piglowski W, Lorenc Z, Muc-Wierzgon M, Nowakowska-Zajdel E (2016) A novel quantitative method of pten expression assessment in tumor tissue. J Biol Regul Homeost Agents 30: 79-90.

https://www.ncbi.nlm.nih.gov/pubmed/27049078

Widlak P, Mrukwa G, Kalinowska M, Pietrowska M, Chekan M, Wierzgon J, Gawin M, Drazek G, Polanska J (2016) Detection of molecular signatures of oral squamous cell carcinoma and normal epithelium - application of a novel methodology for unsupervised segmentation of imaging mass spectrometry data. Proteomics 16: 1613-1621.

https://www.ncbi.nlm.nih.gov/pubmed/27168173

Widlak P, Pietrowska M, Polanska J, Marczyk M, Ros-Mazurczyk M, Dziadziuszko R, Jassem J, Rzyman W (2016) Serum mass profile signature as a biomarker of early lung cancer. Lung Cancer 99: 46-52.

https://www.ncbi.nlm.nih.gov/pubmed/27565913

Woźniak G, Herok R, Jaksik R, Misiołek M, Kolebacz B, Fiszer-Kierzkowska A, Miśkiewicz-Orczyk K, Szymczyk C, Maciejewski A, Głowacki G, Suwiński R (2016) Cell-cycle gene expression analysis using real time PCR in locally advanced squamous-cell head and neck cancer. Adv Med Sci. 61: 293-299.

https://www.ncbi.nlm.nih.gov/pubmed/27136187

Zięba A, Latocha M, Sochanik A, Nycz A, Kuśmierz D (2016) Synthesis and in vitro antiproliferative activity of novel phenyl ring-substituted 5-alkyl-12(H)-quino[3,4-b][1,4]benzothiazine Derivatives. Molecules 21. pii: E1455.

https://www.ncbi.nlm.nih.gov/pubmed/27827930

 

2015 

Abramowicz A, Wojakowska A, Gdowicz-Klosok A, Polanska J, Rodziewicz P, Polanowski P, Namysl-Kaletka A, Pietrowska M, Wydmanski J, Widlak P (2015) Identification of serum proteome signatures of locally advanced and metastatic gastric cancer: a pilot study. J Transl Med 13:e304.

http://www.ncbi.nlm.nih.gov/pubmed/26376850 

Butkiewicz D, Krześniak M, Drosik A, Giglok M, Gdowicz-Kłosok A, Kosarewicz A, Rusin M, Masłyk B, Gawkowska-Suwińska M, Suwiński R. (2015) The VEGFR2, COX-2 and MMP-2 polymorphisms are associated with clinical outcome of patients with inoperable non-small cell lung cancer. Int J Cancer 137:2332-42.

http://www.ncbi.nlm.nih.gov/pubmed/25975224

Chorąży M (2015) Zjawisko samoorganizacji jako element ewolucji życia. Nauka 2/2015, 127-146.

http://nauka-pan.pl/index.php/nauka/article/viewFile/81/78

Gadher SJ, Marczak Ł, Łuczak M, Stobiecki M, Widlak P, Kovarova H (2015) Proteomic landscape in Central and Eastern Europe: the 9th Central and Eastern European Proteomic Conference, Poznań, Poland. Expert Rev Proteomics 2015:1-3. 

http://www.ncbi.nlm.nih.gov/pubmed/26558656

Gdowicz-Kłosok A, Giglok M, Drosik A, Suwiński R, Butkiewicz D. (2015) The SIPA1-313A>G polymorphism is associated with prognosis in inoperable non-small cell lung cancer. Tumour Biol 36:1273-78.

http://www.ncbi.nlm.nih.gov/pubmed/25352027

Gramatyka M, Widłak P (2015) Neither resveratrol nor metformin protects human cardiomyocytes against toxicity of epirubicin and radiation in-vitro. Medical Science, 2015,17(67):1-10.

http://discoveryjournals.com/medicalscience/current_issue/v17/n67/A1.pdf

Habryka A,  Gogler-Pigłowska  A,  Sojka D, Kryj M, Krawczyk Z,  Ścieglińska D (2015) Cell type-dependent modulation of the gene encoding heat shock protein HSPA2 by hypoxia-inducible factor HIF-1: down-regulation in keratinocytes and up-regulation in HeLa cells. Biochim Biophys Acta 1849:1155-69.

http://www.ncbi.nlm.nih.gov/pubmed/26164067 

Janus P, Stokowy T, Jaksik R, Szoltysek K, Handschuh L, Podkowinski J, Widlak W, Kimmel M, Widlak P (2015) Cross talk between cytokine and hyperthermia-induced pathways: identification of different subsets of NF-κB-dependent genes regulated by TNFα and heat shock. Mol Genet Genomics 290:1979-90.

http://www.ncbi.nlm.nih.gov/pubmed/25944781 

Jarosz-Biej M, Smolarczyk R, Cichoń T, Kułach N, Czapla J, Matuszczak S, Szala S (2015) Combined Tumor Cell-Based Vaccination and Interleukin-12 Gene Therapy Polarizes the Tumor Microenvironment in Mice. Arch Immunol Ther Exp 63:451-64.

http://www.ncbi.nlm.nih.gov/pubmed/25801067  

Jelonek K, Wojakowska A, Marczak L, Muer A, Tinhofer-Keilholz I, Lysek-Gladysinska M, Widlak P, Pietrowska M (2015) Ionizing radiation affects protein composition of exosomes secreted in vitro from head and neck squamous cell carcinoma. Acta Biochim Pol 62:265-72.

http://www.ncbi.nlm.nih.gov/pubmed/26098714 

Kujawa KA, Lisowska KM (2015) Rak jajnika – od biologii do kliniki. Post Hig Med Dosw 69:1275-90.

http://www.phmd.pl/abstracted.php?level=5&ICID=1184451 

Materska M, Konopacka M, Rogoliński J, Ślosarek K (2015) Antioxidant activity and protective effects against oxidative damage of human cells induced by X-radiation of phenolic glycosides isolated from pepper fruits Capsicum annuum L. Food Chem. 168:546-53.

http://www.ncbi.nlm.nih.gov/pubmed/25172746 

Mazurek A, Pierzyna M, Giglok M, Dworzecka U, Suwiński R, Malusecka E (2015) Quantification of concentration and assessment of EGFR mutation in circulating DNA. Cancer Biomark 15:515-24.

http://www.ncbi.nlm.nih.gov/pubmed/25769456 

Pamuła-Piłat J, Tęcza K, Nie tylko BRCA-geny umiarkowanego ryzyka w raku piersi, Laboratorium, 7-8/2015.

http://laboratorium.elamed.pl/uploads/lab/articles/25707/05.pdf 

Pietrowska M, Jelonek K, Polanska J, Wojakowska A, Marczak L, Chawinska E, Chmura A, Majewski W, Miszczyk L, Widlak P (2015) Partial-body irradiation in patients with prostate cancer treated with IMRT has little effect on the composition of serum proteome. Proteomes 3:117-31.

http://www.mdpi.com/2227-7382/3/3/117   

Polanski A, Marczyk M, Pietrowska M, Widlak P, Polanska J (2015) Signal partitioning algorithm for highly efficient Gaussian Mixture Modeling in mass spectrometry. PLoS One 10:e0134256.

http://www.ncbi.nlm.nih.gov/pubmed/26230717 

Rusinek D, Swierniak M, Chmielik E, Kowal M, Kowalska M, Cyplinska R, Czarniecka A, Piglowski W, Korfanty J, Chekan M, Krajewska J, Szpak-Ulczok S, Jarzab M, Widlak W, Jarzab B (2015) BRAFV600E-associated gene expression profile: early changes in the transcriptome, based on a transgenic mouse model of papillary thyroid carcinoma. PLoS One 10:e0143688.

http://www.ncbi.nlm.nih.gov/pubmed/26625260  

Ścieglińska D, Krawczyk Z (2015) Expression, funkction and regulation of the testis-enriched heat shock, HSPA2 gene in rodents and humans. Cell Stress Chaperones 20:221-235.

http://www.ncbi.nlm.nih.gov/pubmed/25344376  

Snietura M, Rutkowski T, Piglowski W, Hajduk A, Wygoda A, Skladowski K, Lange D. (2015): Human papillomavirus DNA in pharyngeal scrapes as a marker of HPV-related squamous cell cancer of the oropharynx. J Clin Virol 71:34-39.

http://www.ncbi.nlm.nih.gov/pubmed/26370312  

Szafron LM, Balcerak A, Grzybowska EA, Pienkowska-Grela B, Podgorska A, Zub R, Olbryt M, Pamula-Pilat J, Lisowska KM, Grzybowska E, Rubel T, Dansonka-Mieszkowska A, Konopka B, Kulesza M, Lukasik M, Kupryjanczyk J (2015) The putative oncogene, CRNDE, is a negative prognostic factor in ovarian cancer patients. Oncotarget 2015 Nov epub ehead of print.

http://www.ncbi.nlm.nih.gov/pubmed/26556866  

Szala S, Jarosz-Biej M, Cichoń T, Smolarczyk R, Sochanik A (2015) Polarization of tumor milieu: therapeutic implications. N. Rezaei (ed.), Cancer Immunology: Bench to Bedside Immunotherapy of Cancers. Chapter 22, pp. 401-408. Springer-Verlag Berlin Heidelberg 2015. DOI 10.1007/978-3-662-44946-2_22.

http://link.springer.com/chapter/10.1007/978-3-662-44946-2_22 

Tecza K, Pamula-Pilat J, Kolosza Z, Radlak N, Grzybowska E (2015) Genetic polymorphisms and gene-dosage effect in ovarian cancer risk and response to paclitaxel/cisplatin chemotherapy. J Exp Clin Cancer Res 34:2

http://www.ncbi.nlm.nih.gov/pubmed/25591549  

Toma-Jonik A, Widlak W, Korfanty J, Cichon T, Smolarczyk R, Gogler-Piglowska A, Widlak P, Vydra N (2015) Active heat shock transcription factor 1 supports migration of the melanoma cells via vinculin down-regulation. Cell Signal 27:394-401.

http://www.ncbi.nlm.nih.gov/pubmed/25435429 

Tóth E, Vékey K, Ozohanics O, Jekő A, Dominczyk I, Widlak P, Drahos L (2015) Changes of protein glycosylation in the course of radiotherapy. J Pharm Biomed Anal 118:380-6.

http://www.ncbi.nlm.nih.gov/pubmed/26609677  

Widłak P, Jelonek K, Wojakowska M, Pietrowska M, Polanska J, Marczak L, Miszczyk L, Składowski K (2015) Serum proteome signature of radiation response: upregulation of inflammation-related factors, and downregulation of apolipoproteins and coagulation factors in cancer patients subjected to radiotherapy – a pilot study. Int J Radiat Oncol Biol Phys 92:1108-15.

http://www.ncbi.nlm.nih.gov/pubmed/26031365 

Wojakowska A, Chekan M, Marczak Ł, Polanski K, Lange D, Pietrowska M, Widlak P (2015) Detection of metabolites discriminating subtypes of thyroid cancer: molecular profiling of FFPE samples using the GC/MS approach. Mol Cell Endocrinol 417: 149-57.

http://www.ncbi.nlm.nih.gov/pubmed/26415588 

Wojakowska A, Chekan M, Widłak P, Pietrowska M (2015) Application of metabolomics in thyroid cancer research. Int J Endocrinol 2015:258763.

http://www.ncbi.nlm.nih.gov/pubmed/25972898 

Wojakowska A, Marczak Ł, Jelonek K, Polanski K, Widlak P, Pietrowska M (2015) An optimized method of metabolite extraction from formalin-fixed paraffin-embedded tissue for GC/MS analysis. PLoS One 10:e0136902.

http://www.ncbi.nlm.nih.gov/pubmed/26348873 

Zajkowicz A, Butkiewicz D, Drosik A, Giglok M, Suwiński R, Rusin M. (2015) Truncating mutations of PPM1D are found in blood DNA samples of lung cancer patients. Br J Cancer 112:114-20.

http://www.ncbi.nlm.nih.gov/pubmed/25742468  

Zajkowicz A, Gdowicz-Kłosok A, Krześniak M, Ścieglińska D, Rusin M. (2015) Actinomycin D and nutlin-3a synergistically promote phosphorylation of p53 on serine 46 in cancer cell lines of different origin. Cell Signal. 27:1677-87.

http://www.ncbi.nlm.nih.gov/pubmed/25989210  

 

2014

Cichoń T, Smolarczyk R, Matuszczak S, Barczyk M, Jarosz M, Szala S (2014) D-K6L 9 Peptide combination with IL-12 inhibits the recurrence of tumors in mice. Arch Immunol Ther Exp (Warsz) 62:341-351.

http://www.ncbi.nlm.nih.gov/pubmed/24487722

Ciomber A, Smagur A, Mitrus I, Cichoń T, Smolarczyk R, Sochanik A, Szala S, Jarosz M (2014) Antitumor effects of recombinant antivascular protein ABRaA-VEGF121 combined with IL-12 gene therapy. Arch Immunol Ther Exp 62: 161-168.

http://www.ncbi.nlm.nih.gov/pubmed/24220932

Frąckowiak-Wojtasek B, Gąsowska-Bajger B, Mazurek M, Raniszewska A, Logghe M, Smolarczyk R, Cichoń T, Szala S, Wojtasek H (2014) Synthesis and analysis of activity of a potential anti-melanoma prodrug with a hydrazine linker. Eur J Med Chem. 71:98-104.

http://www.ncbi.nlm.nih.gov/pubmed/24287558

Giebel S, Boratyn-Nowicka A, Karabon L, Jedynak A, Pamula-Pilat J, Tecza K, Kula D, Kowal M, Frydecka I, Grzybowska E (2014) Associations between genes for killer immunoglobulin-like receptors and their ligands in patients with epithelial ovarian cancer. Hum Immunol. 75:508-513.

http://www.ncbi.nlm.nih.gov/pubmed/24755350

Gruca A, Krawczyk Z, Szeja W, Grynkiewicz G, Rusin A (2014) Synthetic genistein glycosides inhibiting EGFR phosphorylation enhance the effect of radiation in HCT 116 colon cancer cells. Molecules, 19:18558-18573.

http://www.ncbi.nlm.nih.gov/pubmed/25401399

Jelonek K, Pietrowska M, Ros M, Zagdanski A, Suchwalko A, Polanska J, Marczyk M, Rutkowski T, Skladowski K, Clench MR, Widlak P (2014) Radiation-induced changes in serum lipidome of head and neck cancer patients. Int J Mol Sci 15:6609-6624.

http://www.ncbi.nlm.nih.gov/pubmed/24747595

Korfanty J, Stokowy T, Widlak P, Gogler-Piglowska A, Handschuh L, Podkowiński J,  Vydra N, Naumowicz A, Toma A, Widlak W (2014) Crosstalk between HSF1 and HSF2 during the heat shock response in mouse testes. Int J Biochem Cell Biol. 57:76-83.

http://www.ncbi.nlm.nih.gov/pubmed/25450459

Krześniak M, Zajkowicz A, Matuszczyk I, Rusin M. (2014) Rapamycin prevents strong phosphorylation of p53 on serine 46 and attenuates activation of the p53 pathway in A549 lung cancer cells exposed to actinomycin D. Mech Ageing Dev. 139:11-21.

http://www.ncbi.nlm.nih.gov/pubmed/24915467

Lisowska KM, Olbryt M, Dudaladava V, Pamuła-Piłat J, Kujawa K, Grzybowska E, Jarząb M, Student S, Rzepecka IK, Jarząb B, Kupryjańczyk J (2014) Gene expression analysis in ovarian cancer - faults and hints from DNA microarray study. Front Oncol. 4:6.

http://www.ncbi.nlm.nih.gov/pubmed/24478986

Lisowska K, Cortez JA (2014) Kontrowersje wokół długoterminowych badań Gillesa-Erica Seraliniego nad bezpieczeństwem zdrowotnym kukurydzy GMO. Studia Ecologiae et Bioethicae UKSW 12:33-54

http://seib.uksw.edu.pl/node/115

Matuszczak S, Czapla J, Jarosz-Biej M, Wiśniewska E, Cichoń T, Smolarczyk R, Kobusińska M, Gajda K, Wilczek P, Sliwka J, Zembala M, Zembala M, Szala S. (2014) Characteristic of c-Kit+ progenitor cells in explanted human hearts. Clin Res Cardiol. 103:711-718.

http://www.ncbi.nlm.nih.gov/pubmed/24722830

Oduwole OO, Vydra N, Wood NE, Samanta L, Owen L, Keevil B, Donaldson M, Naresh K, Huhtaniemi IT (2014) Overlapping dose responses of spermatogenic and extragonadal testosterone actions jeopardize the principle of hormonal male contraception. FASEB J. 28:2566-2576.

http://www.ncbi.nlm.nih.gov/pubmed/24599970

Olbryt M., Habryka A., Jarząb M., Student S., Tyszkiewicz T., Lisowska K (2014) Global gene expression profiling in three tumor cell lines subjected to experimental cycling and chronic hypoxia. PLOS One 9:e105104.

http://www.ncbi.nlm.nih.gov/pubmed/25122487

Pamuła-Piłat J, Rubel T, Rzepecka IK, Olbryt M, Herok R, Dansonka-Mieszkowska A, Grzybowska E, Kupryjańczyk J (2014) Gene expression profiles in three histologic types, clear-cell, endometrioid and serous ovarian carcinomas. J Biol Regul Homeost Agents 28:659-674.

http://www.ncbi.nlm.nih.gov/pubmed/25620176

 Pamuła-Piłat J, Tęcza K (2014) Chemioterapia raka piersi – efekty uwarunkowane genetycznie, Laboratorium – Przegląd Ogólnopolski,  3-4/2014, 32-39.

http://laboratorium.elamed.pl/archiwum[wydanie,17317,3,2014]

Pietrowska M, Jelonek K, Michalak M, Roś M, Rodziewicz P, Chmielewska K, Polański K, Polańska J, Gdowicz-Kłosok A, Giglok M, Suwiński R, Tarnawski R, Dziadziuszko R, Rzyman W, Widłak P (2014) Identification of serum proteome components associated with progression of non-small cell lung cancer. Acta Biochim Pol. 61:325-331.

http://www.ncbi.nlm.nih.gov/pubmed/24872961

Ścieglinska D, Gogler-Pigłowska A, Butkiewicz D, Chekan M, Malusecka E, Harasim J, Habryka A, Krawczyk Z. (2014) HSPA2 is expressed in human tumors and correlates with clinical features in non-small cell lung carcinoma patients. Anticancer Res. 34:2833-2840.

http://www.ncbi.nlm.nih.gov/pubmed/24922646

Ślosarek K, Konopacka M, Rogoliński J, Sochanik A (2014) Effect of dose rate and irradiation geometry on biological response of normal and cancer cells under radiotherapeutic condition. Mutat Res Genet Toxicol Environ Mutagen 773:14-22.

http://www.ncbi.nlm.nih.gov/pubmed/25308701

Śnietura M, Waniczek D, Pigłowski W, Kopec A, Nowakowska-Zajdel E, Lorenc Z, Muc-Wierzgon M (2014) Potential role of human papilloma virus in the pathogenesis of gastric cancer. World J Gastroenterol. 20:6632-6637.

http://www.ncbi.nlm.nih.gov/pubmed/24914388

Szala S, Matuszczak S, Czapla J, Wiśniewska E. (2014) From precursor to reprogrammed cells: evolution of cardiomyoplasty. Postepy Hig Med Dosw 68:153-161.

http://www.ncbi.nlm.nih.gov/pubmed/24988634

Szala S, Wiśniewska E, Matuszczak S, Czapla J (2014) Mesenchymal Stromal Cells. Postępy Hig. Med. Dośw. 68:1287-1298.

http://www.ncbi.nlm.nih.gov/pubmed/25404618

Szeja W, Grynkiewicz G, Bieg T, Swierk P, Byczek A, Papaj K, K R, Rusin A, (2014) Synthesis and cytotoxicity of 2,3-enopyranosyl C-linked conjugates of genistein, Molecules, 19:7072-7093.

http://www.ncbi.nlm.nih.gov/pubmed/24886936

Tęcza K, Pamuła-Piłat J (2014) Trombocytoza w raku jajnika. Laboratorium – Przegląd Ogólnopolski, 9-10/2014, 47-50.

http://laboratorium.elamed.pl/uploads/lab/articles/21377/lab-9-10-net-5.pdf

Vydra N, Toma A, Widlak W (2014) Pleiotropic role of HSF1 in neoplastic transformation. Curr Cancer Drug Targets 14:144-155.

http://www.ncbi.nlm.nih.gov/pubmed/24467529

Chorąży M, Hancock R. Translational research: lost in complexity. In: Lost in Translation. Barriers to Incentives for Translational Research in Medical Sciences, R. Srivastava, W. Maksymowicz, W. Lopaczynski (eds), World Scientific Publishing Co. 2014, Chapter 1, pp. 3-20, ISBN: 978-981-4489-06-5.

http://www.worldscientific.com/worldscibooks/10.1142/8782

Lisowska K (2014) Socio-economic and safety reasons of rejection of biotechnological and GMO products. In: Biotechnology and Plant Breeding Perspectives, Eds. R.K. Behl and Edward Arseniuk, Agrobios (International) Publisher, Jodhpur, India pp 45-50, ISBN 978-93-81191-01-9.

 

2013

Byczek A, Zawisza-Puchalka J, Gruca A, Papaj K, Grynkiewicz G, Rusin M, Szeja W, Rusin A (2013): Genistein derivatives regioisomerically substituted at 7-O- and 4′-O- have different effect on the cell cycle. J Chemistry 2013: ID 191563

http://www.hindawi.com/journals/jchem/2013/191563/

Gdowicz-Klosok A, Widel M, Rzeszowska-Wolny J (2013) The influence of XPD, APE1, XRCC1, and NBS1 polymorphic variants on DNA repair in cells exposed to X-rays. Mutat Res 755: 42-48.

http://www.ncbi.nlm.nih.gov/pubmed/23669291

Głowala-Kosińska M, Chwieduk A, Nieckula J, Saduś-Wojciechowska M, Grosicki S, Rusin A, Nowara E, Giebel S (2013) Association of circulating regulatory T cell number with the incidence and prognosis of diffuse large B-cell lymphoma. Eur J Haematol  91: 122-128.

http://www.ncbi.nlm.nih.gov/pubmed/23679234

Huzarski T, Cybulski C, Jakubowska A, Byrski T, Gronwald J, Domagała P, Szwiec M, Godlewski D, Kilar E, Marczyk E, Siołek M, Gorski B, Wiśniowski R, Janiszewska H, Surdyka D, Sibilski R, Sun P, Narod SA, Lubiński J; Collaborators: Błasińska-Morawiec M, Chosia M, Drosik K, Gozdecka-Grodecka S, Goźdź S, Grzybowska E, et al., (2013): Clinical characteristics of breast cancer in patients with an NBSl mutation.  Polish Breast Cancer Consortium. Breast Cancer Res Tr, 141: 471-476.

http://www.ncbi.nlm.nih.gov/pubmed/24072268

Jarosz M, Jazowiecka-Rakus J, Cichoń T, Głowala-Kosińska M, Smolarczyk R, Smagur A, Malina S, Sochanik A, Szala S (2012): Therapeutic antitumor potential of endoglin-based DNA vaccine combined with immunomodulatory agents. Gene Ther 20: 262-273.

http://www.ncbi.nlm.nih.gov/pubmed/22495576

Jarosz M, Szala S (2013) Endoglin as a target of antitumor therapy. Post Hig Med Dosw 67: 79-89.

http://www.ncbi.nlm.nih.gov/pubmed/23475485 

Jelonek K, Roś M, Pietrowska M, Widłak P (2013): Cancer biomarkers and mass spectrometry-based analyses of phospholipids in body fluids. Clin Lipidol 8: 137-150

http://www.futuremedicine.com/doi/abs/10.2217/clp.12.79

Kalinowska-Herok M, Pietrowska M, Walaszczyk A, Widłak P (2013): MALDI imaging mass spectrometry – a novel approach in biomedical research of tissues. Curr Proteomics 10: 76-82.

http://benthamscience.com/journal/abstracts.php?journalID=cp&articleID=113842 

Kus-Liskiewicz MG, Polanska J, Korfanty J, Olbryt M, Vydra N, Toma A, Widlak WA (2013) Impact of heat shock transcription factor 1 on global gene expression profiles in cells which induce either cytoprotective or pro-apoptotic response following hyperthermia. BMC Genomics 14: 456.

http://www.ncbi.nlm.nih.gov/pubmed/23834426

Mazurek AM, Fiszer-Kierzkowska A, Rutkowski T, Pierzyna M, Ścieglińska D, Woźniak G,  Głowacki G, Kawczyński R, Składowski K, Małusecka E (2013): Optimization of circulating cell-free DNA recovery for KRAS mutation and HPV detection in plasma. Cancer Biomark 13: 385-394.

http://www.ncbi.nlm.nih.gov/pubmed/24440979

Mielzynska-Svach D, Blaszczyk E, Butkiewicz D, Durzynska J, Rydzanicz M. (2013): Influence of genetic polymorphisms on biomarkers of exposure and effects in children living in Upper Silesia. Mutagenesis 28: 591-599.

http://www.ncbi.nlm.nih.gov/pubmed/23867956

Olbryt M (2013): Role of tumor microenvironment in the formation and progression of skin melanoma. Post Hig Med Dosw 67: 413-432.

http://www.ncbi.nlm.nih.gov/pubmed/23756376

Rusin A, Chrubasik M, Papaj K, Grynkiewicz G, Szeja W (2013): C-Glycosidic genistein conjugates and their antiproliferative activity. J Chem 2013: ID 951392.

http://www.hindawi.com/journals/chem/2013/951392/

Szeja W, Swierk P, Grynkiewicz G, Rusin A, Papaj K (2013):  An approach to C-glycosidic conjugates of isoflavones. Heterocyclic Commun 19: 133-138.

http://www.degruyter.com/view/j/hc.2013.19.issue-2/hc-2013-0023/hc-2013-0023.xml?format=INT

Szultka M, Papaj K, Rusin A, Szeja W, Buszewski B (2013): Determination of flavonoids and their metabolites by chromatographic techniques. Trends Anal Chem 47: 47-67.

http://www.sciencedirect.com/science/article/pii/S0165993613000757

Tan DS, Yap TA, Hutka M, Roxburgh P, Ang J, Banerjee S, Grzybowska E, Gourley C, Gore ME, Kaye SB (2013): Implications of BRCA1 and BRCA2 mutations for the efficacy of paclitaxel monotherapy in advanced ovarian cancer. Eur J Cancer 49: 1246-1253.

http://www.ncbi.nlm.nih.gov/pubmed/23265709

Vydra N, Toma A, Glowala-Kosinska M, Gogler-Piglowska A, Widlak W (2013): Overexpression of heat shock transcription factor 1 enhances the resistance of melanoma cells to doxorubicin and paclitaxel. BMC Cancer 29:13:504.

http://www.ncbi.nlm.nih.gov/pubmed/24165036

Waniczek D, Śnietura M, Młynarczyk-Liszka J, Pigłowski W, Kopeć A, Lange D, Rudzki M, Arendt J (2013): PTEN expression profiles in colorectal adenocarcinoma and its precancerous lesions. Pol J Pathol. 64:15-20.

http://www.ncbi.nlm.nih.gov/pubmed/23625595

Widłak P, Pietrowska M, Polańska J, Rutkowski T,  Jelonek K, Kalinowska-Herok M,  Gdowicz-Kłosok A, Wygoda W, Tarnawski R, Składowski K (2013): Radiotherapy-related changes in serum proteome patterns of head and neck cancer patients; the effect of low and medium doses of radiation delivered to large volumes of normal tissue. J Transl Med 11: e299.

http://www.ncbi.nlm.nih.gov/pubmed/24304975

Wilczek PM, Zembala M, Zembala M, Mzyk A, Cichoń T, Smolarczyk R (2013): Cardiac stem and progenitor cells as a potential therapeutic agent for the treatment of damaged cardiac muscle. Pol J Thor Cardiovasc Surg 10: 51-61.

Polish Journal of Thoracic and Cardiovascular Surgery

http://www.termedia.pl/EXPERIMENTAL-CARDIOVASCULAR-AND-LUNG-RESEARCH-Cardiac-stem-and-progenitor-cells-as-a-potential-therapeutic-agent-for-the-treatment-of-damaged-cardiac-muscle,40,20520,0,0.html

Zajkowicz A, Krześniak M, Matuszczyk I, Głowala-Kosińska M, Butkiewicz D, Rusin M (2013): Nutlin-3a, an MDM2 antagonist and p53 activator, helps to preserve the replicative potential of cancer cells treated with a genotoxic dose of resveratrol. Mol Biol Rep 40: 5013-5026.

http://www.ncbi.nlm.nih.gov/pubmed/23666059

 

2012

Varadi V, Bevier M, Grzybowska E, Johansson R, Enquist-Olsson K, Henriksson R, Butkiewicz D, Pamuła-Piłat J, Tęcza K, Hemminki K, Lenner P, Försti A (2012): Genetic variation in ALCAM and other chromosomal instability genes in breast cancer survival. Breast Cancer Res Treat 131: 311-319.

http://www.ncbi.nlm.nih.gov/pubmed/21935604

Harlid S, Ivarsson MI, Butt S, Grzybowska E, Eyfjörd JE, Lenner P, Försti A, Hemminki K, Manjer J, Dillner J, Carlson J (2012): Combined effect of low-penetrant SNPs on breast cancer risk. Br J Cancer 106: 389-396.

http://www.ncbi.nlm.nih.gov/pubmed/22045194

Wideł M, Przybyszewski WM, Cieslar-Pobuda A, Saenko YV, Rzeszowska-Wolny J (2012): Bystander normal human fibroblasts reduce damage response in radiation targeted cancer cells through intercellular ROS level modulation. Mutat Res 731: 117-124.

http://www.ncbi.nlm.nih.gov/pubmed/22210495

Budryk M, Pamuła-Piłat J, Tęcza K, Grzybowska E (2012): Spectrum of tumors in the families with Hereditary Breast Ovarian Cancer syndrome carrying germline mutations in BRCA1 and 2 genes. Hered Cancer Clin Pract 10, Suppl 1: A2

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287435/pdf/1897-4287-10-S1-A2.pdf

Mazurek AM, Olbryt M (2012): The influence of neuropilin-1 silencing on semaphorin 3A and 3C activity in B16(F10) murine melanoma cells. Neoplasma 59: 43-51.

http://www.ncbi.nlm.nih.gov/pubmed/22082309

Pietrowska M, Polańska J, Suwiński R, Wideł M, Rutkowski T, Marczyk M, Marczak L, Polański A, Widłak P (2012): Comparison of peptide cancer signatures identified by mass spectrometry in serum of patients with head and neck, lung, and colorectal cancers. Int J Oncol 40: 148-156.

http://www.ncbi.nlm.nih.gov/pubmed/21894432

Filipczak PT, Piglowski W, Glowala-Kosinska M, Krawczyk Z, Scieglinska D (2012): HSPA2 overexpression protects V79 fibroblasts against bortezomib-induced apoptosis. Biochem Cell Biol 90: 224-231.

http://www.ncbi.nlm.nih.gov/pubmed/22397456

Korfanty J, Toma A, Wojtas A, Rusin A, Vydra N, Widlak W (2012): Identification of a new mouse sperm acrosome-associated protein. Reproduction 43: 749-757.

http://www.ncbi.nlm.nih.gov/pubmed/22495889

Nawalany K, Rusin A, Kepczynski M, Filipczak P, Kumorek M, Kozik B, Weitman H, Ehrenberg B, Krawczyk Z, Nowakowska M (2012): Novel nanostructural photosensitizers for photodynamic therapy: In vitro studies. Int J Pharm 430: 129 140.

http://www.ncbi.nlm.nih.gov/pubmed/22525077

Dobrut M, Jaremko M, Konopacka M, Rogoliński J, Dobosz T (2012): Preliminary genetic investigation of the patient with atypical long (55 years) malignant melanoma process. PrzypadkiMedyczne.pl 3: 118-124.

http://www.przypadkimedyczne.pl/czasopismo/papers/29-2012-abstract.pdf

Gogler-Pigłowska A, Rusin A, Bochenek D, Krawczyk Z (2012): Aneugenic effects of the genistein glycosidic derivative substituted at C7 with the unsaturated disaccharide. Cell Biol Toxicol 28: 331-342.

http://www.ncbi.nlm.nih.gov/pubmed/22843076

Smolarczyk R, Cichoń T, Matuszczak S, Mitrus I, Lesiak M, Kobusińska M, Kamysz W, Jarosz M, Sieroń A, Szala S (2012): The role of glycyrrhizin, an inhibitor of HMGB1 protein, in anticancer therapy. Arch Immunol Ther Exp 60: 391-399.

http://www.ncbi.nlm.nih.gov/pubmed/22922889

Mitrus I, Bryndza E, Kazura M, Smagur A, Sochanik A, Cichon T, Szala S (2012): Properties of B16-F10 murine melanoma cells subjected to metabolic stress conditions. Acta Biochim Pol 59: 363-366.

http://www.ncbi.nlm.nih.gov/pubmed/22910557

Cichoń T, Jarosz M, Smolarczyk R, Ogórek B, Matuszczak S, Wagner M, Mitrus I, Sochanik A, Jazowiecka-Rakus J, Szala S (2012): Vasostatin increases oxygenation of B16-F10 melanoma tumors and raises therapeutic efficacy of cyclophosphamide. Acta Biochim Pol 59: 377-381.

http://www.ncbi.nlm.nih.gov/pubmed/22946026

Mitrus I, Bryndza E, Sochanik A, Szala S (2012): Evolving models of tumor origin and progression. Tumour Biol 33: 911-917.

http://www.ncbi.nlm.nih.gov/pubmed/22492238

Wilczek P, Zembala M, Cichoń T, Smolarczyk R, Szala S, Zembala M (2012): Konstrukcja rusztowań dla efektywnego transferu komórek macierzystych serca do uszkodzonego mięśnia sercowego. Kardiochirurgia i Torakochirurgia Polska 2: 231-242.

http://www.termedia.pl/BADANIA-KLINICZNE-I-DOSWIADCZALNE-W-CHOROBACH-SERCA-PLUC-I-NACZYN-Konstrukcja-rusztowan-dla-efektywnego-transferu-komorek-macierzystych-serca-do-uszkodzonego-miesnia-sercowego,40,18934,0,0.html

Śliwka J, Kumaszka B, Garbacz M, Pakuło S, Nowak K, Domagała M, Jaźwiec T,  Mandecki M, Cichoń T, Nożyński J, Smolarczyk R, Szala S, Zembala M, Zembala M (2012): Zawał mięśnia sercowego u myszy – jak stworzyć dobrze funkcjonujący model doświadczalny. Kardiochirurgia i Torakochirurgia Polska 2: 243-251.

http://www.termedia.pl/Zawal-miesnia-sercowego-u-myszy-jak-stworzyc-dobrze-funkcjonujacy-model-doswiadczalny,40,18935,0,0.html

Szala S, Jarosz M, Smolarczyk R, Cichoń T (2012): "Vicious circles" of glioblastoma tumors: vascularization and invasiveness. Post Hig Med Dosw 66: 888-900.

http://www.ncbi.nlm.nih.gov/pubmed/23175345

Smolarczyk R, Cichoń T, Jarosz M, Szala S (2012): HMGB1 – its role in tumor progression and anticancer therapy. Post Hig Med Dosw 66: 913-920.

http://www.ncbi.nlm.nih.gov/pubmed/23175347

Serda M, Kalinowski DS, Mrozek-Wilczkiewicz A, Musiol R, Szurko A, Ratusza A, Pantarat N, Kovacevic Z, Merlot AM, Richardson DR, Polanski J (2012) Synthesis and characterization of quinoline-based thiosemicarbazones and correlation of cellular iron-binding efficacy to anti-tumor efficacy. Bioorg Med Chem Lett 22: 5527-5531.

http://www.ncbi.nlm.nih.gov/pubmed/22858101

Pietrowska M, Widłak P (2012) MALDI-MS-based profiling of serum proteome: detection of changes related to progression of cancer and response to anticancer treatment. Int J Proteomics 2012:926427.

http://www.ncbi.nlm.nih.gov/pubmed/22900176

Butkiewicz D, Drosik A, Suwiński R, Krześniak M, Rusin M, Kosarewicz A, Rachtan J, Matuszczyk I, Gawkowska-Suwińska M (2012) Influence of DNA repair gene polymorphisms on prognosis in inoperable non-small cell lung cancer patients treated with radiotherapy and platinum-based chemotherapy. Int J Cancer 131: E1100-1108.

http://www.ncbi.nlm.nih.gov/pubmed/22511383

Snietura M, Jaworska M, Mlynarczyk-Liszka J, Goraj-Zajac A, Piglowski W, Lange D, Wozniak G, Nowara E, Suwinski R (2012) PTEN as a prognostic and predictive marker in postoperative radiotherapy for squamous cell cancer of the head and neck. PLoS One 7:e33396.

http://www.ncbi.nlm.nih.gov/pubmed/22413021

Małodobra M, Paduch A, Lebioda A, Konopacka M, Rogoliński J, Szymczyk C, Wierzgoń J, Maciejewski A, Chmielik E, Jonkisz A, Półtorak S (2012) VDR gene single nucleotide polymorphisms and their association with risk of oral cavity carcinoma. Acta Biochim Polon 59: 627-630.

http://www.ncbi.nlm.nih.gov/pubmed/23189278

Goj K, Rusin A, Szeja W, Kitel R, Komor R, Grynkiewicz G (2012) Synthesis of genistein 2,3-anhydroglycoconjugates – potential antiproliferative agents. Acta Pol Pharm. 69: 1239-1247.

http://www.ncbi.nlm.nih.gov/pubmed/23285686

Malusecka E, Fiszer-Kierzkowska A, Herok R, Wronski S, Rembak-Szynkiewicz J (2012) Combining laser-assisted microdisstection with/and immunohistochemistry – RNA quality of clinical LCM-derived samples. J Clinic Experiment Pathol Volume 2:3.

http://www.omicsonline.org/2161-0681/2161-0681-2-112.php?aid=6279%20%20?aid=6259?aid=7323

Varadi V, Bevier M, Grzybowska E, Johansson R, Enquist-Olsson K, Henriksson R, Butkiewicz D, Pamula-Pilat J, Tecza K, Hemminki K, Lenner P, Försti A (2012): Genetic variation in ALCAM and other chromosomal instability genes in breast cancer survival. Breast Cancer Res. Treat  131: 311-319.

http://www.ncbi.nlm.nih.gov/pubmed/21935604

2011

Brozek I, Cybulska C, Ratajska M, Piatkowska M, Kluska A, Balabas A, Dabrowska M, Nowakowska D, Niwinska A, Pamuła-Piłat J, Tęcza K, Pękala W, Rembowska J, Nowicka K, Mosor M, Januszkiewicz-Lewandowska D, Rachtan J, Grzybowska E, Nowak J, Steffen J, Limon J (2011): Prevalence of the most frequent BRCA1 mutations in Polish population. J. Appl. Genet . 52: 325-330.

http://www.ncbi.nlm.nih.gov/pubmed/21503673

Butkiewicz D, Rusin M, Sikora B, Lach A, Chorąży M (2011): An association between DNA repair gene polymorphisms and survival in patients with resected non-small cell lung cancer Mol Biol Rep 38: 52-31.

http://www.ncbi.nlm.nih.gov/pubmed/21188533

Fiszer-Kierzkowska A, Vydra N, Wysocka-Wycisk A, Kronekova Z, Jarzab M, Lisowska K, Krawczyk Z (2011) Liposome-based DNA carriers may induce cellular stress response and change gene expression pattern in transfected cells. BMC Mol. Biol 12: e27.

http://www.ncbi.nlm.nih.gov/pubmed/21663599

Harlid S, Ivarsson MI, Butt S, Hussain S, Grzybowska E, Eyfjörd JE, Lenner P, Försti A, Hemminki K, Manjer J, Dillner J, Carlson J (2011): A candidate CpG SNP approach identifies a breast cancer associated ESR1-SNP. Int. J. Cancer 129: 1689-1698.

http://www.ncbi.nlm.nih.gov/pubmed/21105050

Janus P, Pakuła-Cis M, Kalinowska-Herok M, Kashchak N, Szołtysek K, Pigłowski W, Widlak W, Kimmel M, Widlak P (2011): NF- kappa B signaling pathway is inhibited by heat shock independently of active transcription factor HSF1 and increased levels of inducible heat shock proteins. Genes Cells 16: 1168-1175.

http://www.ncbi.nlm.nih.gov/pubmed/22077664

Jelonek K, Walaszczyk A, Gabryś D, Pietrowska M, Kanthou C, Widłak P (2011): Cardiac endothelial cells isolated from mouse heart - a novel model for radiobiology. Acta Biochim Pol. 58: 397-404.

http://www.ncbi.nlm.nih.gov/pubmed/21887413

Konopacka M, Rogoliński J (2011) Clastogenic effects in human lymphocytes exposed to low and high dose rate X-ray irradiation and vitamic C. Nukleonika 56: 253-257.

http://www.nukleonika.pl/www/back/full/vol56_2011/v56n4p253f.pdf

Konopacka M, Rogoliński J, Slosarek K (2011) Direct and bystander effects induced by scattered radiation generated during penetration of radiation inside a water-phantom. Mutat Res 721: 6-14.

http://www.ncbi.nlm.nih.gov/pubmed/21237284

Lisowska KM, Dudaladava V, Jarzab M, Huzarski T, Chmielik E, Stobiecka E, Lubinski J, Jarzab B (2011): BRCA1-related gene signature in breast cancer: the role of ER status and molecular type. Front. Biosci. 3: 125-136.

http://www.ncbi.nlm.nih.gov/pubmed/21196292

Olbryt M, Habryka A, Tyszkiewicz T, Rusin A, Cichoń T, Jarząb M, Krawczyk Z (2011): Melanoma-associated genes, MXI1, FN1, and NME1, are hypoxia responsive in murine and human melanoma cells. Melanoma Res 21: 417-425.

http://www.ncbi.nlm.nih.gov/pubmed/21912348

Piccinni E, Chelstowska A, Hanus J, Widlak P, Loreti S, Tata AM, Augusti-Tocco G, Bianchi MM, Negri R (2011): Direct interaction of Gas41 and Myc encoded by amplified genes in nervous system tumours. Acta Biochim Pol 58: 529-534.

http://www.ncbi.nlm.nih.gov/pubmed/22068108

Pietrowska M, Polańska J, Walaszczyk A, Wygoda A, Rutkowski T, Składowski K, Marczak L, Stobiecki M, Marczyk M, Polański A, Widłak P (2011): Association between plasma proteome profiles analysed by mass spectrometry, a lymphocyte-based DNA-break repair assay and radiotherapy-induced acute mucosal reaction in head and neck cancer patients. Int J Radiat Biol. 87: 711-719.

http://www.ncbi.nlm.nih.gov/pubmed/21351848

Rupik W, Jasik K, Bembenek J, Widłak W (2011): The expression patterns of heat shock genes and proteins and their role during vertebrate's development. Comp Biochem Physiol A Mol Integr Physiol 159: 349-66.

http://www.ncbi.nlm.nih.gov/pubmed/21527352

Rusin A, Krawczyk Z: Genistein derivatization – from a dietary supplement to a pharmaceutical agent, in: H.A. El-Shemy (Ed.) Soybean and Health, InTech Croatia , 2011, Chapter 12, pp. 253-282.

http://www.intechopen.com/source/pdfs/19752/InTech-Genistein_derivatization_from_a_dietary_supplement_to_a_pharmaceutical_agent.pdf

Rusin A, Zawisza-Puchałka J, Kujawa K, Gogler-Pigłowska A, Wietrzyk J, Switalska M, Głowala-Kosińska M, Gruca A, Szeja W, Krawczyk Z, Grynkiewicz G (2011): Synthetic conjugates of genistein affecting proliferation and mitosis of cancer cells. Bioorg. Med. Chem. 19: 295-305.

http://www.ncbi.nlm.nih.gov/pubmed/21129977

Ścieglińska D, Pigłowski W, Chekan M, Mazurek A, Krawczyk Z (2011) Differential expression of HSPA1 and HSPA2 proteins in human tissues; tissue microarray-based immunohistochemical study. Histochem Cell Biol 135: 337-350.

http://www.ncbi.nlm.nih.gov/pubmed/21373891

Shi H, Bevier M, Johansson R, Grzybowska E, Chen B, Eyfjörd JE, Hamann U, Manjer J, Enquist K, Henriksson R, Carlson J, Brandt A, Lascorz J, Butkiewicz D, Pamula-Pilat J, Tecza K, Herms S, Hoffmann P, Hemminki K, Lenner P, Försti A (2011): Single nucleotide polymorphisms in the 20q13 amplicon genes in relation to breast cancer risk and clinical outcome. Breast Cancer Res Treat 130: 905-916.

http://www.ncbi.nlm.nih.gov/pubmed/21630024

Varadi V, Bevier M, Grzybowska E, Johansson R, Enquist K, Henriksson R, Butkiewicz D, Pamula-Pilat J, Tecza K, Hemminki K, Lenner P, Försti A (2011): Genetic variation in genes encoding for polymerase V subunits associates with breast cancer risk, tumour characteristics and survival. Breast Cancer Res Treat. 129: 235-145.

http://www.ncbi.nlm.nih.gov/pubmed/21455670

Walichiewicz P, Sochanik A, Przybyszewski WM (2011) Influence of local temporary ischemia on radiotherapy effects. J Canc Ther 2: 209-216.

http://www.scirp.org/Journal/PaperInformation.aspx?paperID=5482

Widłak P, Pietrowska M, Wojtkiewicz K, Rutkowski T, Wygoda A, Marczak Ł, Marczyk M, Polańska J, Walaszczyk A, Domińczyk I, Składowski K, Stobiecki M, Polański A (2011): Radiation-related changes in serum proteome profiles detectedby mass spectrometry in blood of patients treated with radiotherapy due to larynx cancer. J Radiat Res. 52: 575-581.

http://www.ncbi.nlm.nih.gov/pubmed/21768750

Zajkowicz A, Rusin M (2011): The activation of the p53 pathway by the AMP mimetic AICAR is reduced by inhibitors of the ATM or mTOR kinases. Mech Ageing Dev 132: 543-551.

http://www.ncbi.nlm.nih.gov/pubmed/21945951

2010

Butkiewicz D, Krześniak M, Vaitiekunaite R, Sikora B, Bowman ED, Harris CC, Rusin M (2010): A functional analysis of G23A polymorphism and the alternative splicing in the expression of the XPA gene. Cell Mol Biol Lett 15: 611-629.

http://www.ncbi.nlm.nih.gov/pubmed/20865363

Byrski T, Gronwald J, Huzarski T, Grzybowska E, Budryk M, Stawicka M, Mierzwa T, Szwiec M, Wiśniowski R, Siołek M, Dent R, Lubiński J, Narod S (2010): Pathologic complete response rates in young women with BRCA1 -positive breast cancers after neoadjuvant chemotherapy. J Clin Oncol 28: 375-379.

http://www.ncbi.nlm.nih.gov/pubmed/20008645

Hanus J, Kalinowska-Herok M, Widłak P (2010): Identification of novel putative regulators of the major apoptotic nuclease DNA Fragmentation Factor. Acta Biochim Polon 57: 521-527.

http://www.ncbi.nlm.nih.gov/pubmed/21152448

Herok R, Konopacka M, Polanska J, Swierniak A, Rogolinski J, Jaksik R, Hancock R, Rzeszowska-Wolny J (2010): Bystander effects induced by medium from irradiated cells: similar transcriptome responses in irradiated and bystander K562 cells. Int J Radiat Oncol Biol Phys 77: 244-252.

http://www.ncbi.nlm.nih.gov/pubmed/20394856

Jelonek K, Gdowicz-Kłosok A, Pietrowska P, Borkowska M, Korfanty J, Rzeszowska-Wolny J, Widłak P (2010): Association between single-nucleotide polymorphisms of selected genes involved in the response to DNA damage and risk of colon, head and neck, and breast cancers in a Polish population. J Appl Genet 51: 343-352.

http://www.ncbi.nlm.nih.gov/pubmed/20720310  

Konopacka M., Rogoliński J (2010): X-irradiation of human bronchial cancer cells causes the bystander effects in normal bronchial cells in vitro. Neoplasma 57: 151-154.

http://www.ncbi.nlm.nih.gov/pubmed/20099979

Langevin SM, Ioannidis JP, Vineis P, Taioli E; Collaborators: Agundez JA, Alexandrie AK, Ankathil R, Autrup H, Autrup JL,Barros-Dios JM, Benhamou S, Boffetta P, Breskvar K, Brockmoller J, Butkiewicz D, et al. (2010): Assessment of cumulative evidence for the association between glutathione S-transferase polymorphisms and lung cancer: application of the Venice interim guidelines. Pharmacogenet. Genomics 20: 586-597.

http://www.ncbi.nlm.nih.gov/pubmed/20729793  

Malusecka E, Gogler A, Gawkowska-Suwinska M, Behrendt K, Nowicka E, Smolska B, Zajusz A (2010): AMACR detection in urine samples; lack of clinical application in routine practice. Open Prostate Cancer . 3: 74-77.

http://www.benthamscience.com/open/topcanj/articles/V003/74TOPCANJ.pdf

Mrozek-Wilczkiewicz A, Kalinowski DS, Musiol R, Finster J, Szurko A, Serafin K, Knas M, Kamalapuram SK, Kovacevic Z, Jampilek J, Ratuszna A, Rzeszowska-Wolny J, Richardson DR, Polanski J (2010) Investigating the anti-proliferative activity of styrylazanaphthalenes and azanaphthalenediones. Bioorg Med Chem 18: 2664-2671.

http://www.ncbi.nlm.nih.gov/pubmed/20303768

Mrozek-Wilczkiewicz A, Kalinowski DS, Musiol R, Finster J, Szurko A, Serafin K, Knas M, Kamalapuram SK, Kovacevic Z, Jampilek J, Ratuszna A, Rzeszowska-Wolny J, Richardson DR, Polanski J. (2010): Investigating the anti-proliferative activity of styrylazanaphthalenes and azanaphthalenediones. Bioorg Med Chem 18: 2664-2671.

http://www.ncbi.nlm.nih.gov/pubmed/20303768

Pietrowska M, Marczak Ł, Polańska J, Nowicka E, Behrendt K, Tarnawski R, Stobiecki M, Polański A, Widłak P (2010): Optimizing of MALDI-ToF-based low-molecular-weight serum proteome pattern analysis in detection of breast cancer patients; the effect of albumin removal on classification performance. Neoplasma 57: 537-544.

http://www.ncbi.nlm.nih.gov/pubmed/20845992

Pietrowska M, Polańska J, Marczak Ł, Behrendt K, Nowicka E, Stobiecki M, Polański A, Tarnawski R, Widłak P (2010): Mass spectrometry-based analysis of therapy-related changes in serum proteome patterns of patients with early stage breast cancer. J Translat Med 8: e66.

http://www.ncbi.nlm.nih.gov/pubmed/20618994

Rusin A, Krawczyk Z, Grynkiewicz G, Gogler A, Zawisza-Puchałka J, Szeja W (2010): Synthetic derivatives of genistein, their properties and possible applications. Acta Biochim Polon. 57: 23-34.

http://www.ncbi.nlm.nih.gov/pubmed/20216977

Smolarczyk R, Cichoń T, Kamysz W, Głowala-Kosińska M, Szydło A, Szultka L, Sieroń AL, Szala S (2010): Anticancer effects of CAMEL peptide. Lab Invest 90: 940-952.

http://www.ncbi.nlm.nih.gov/pubmed/20212453

Sochanik A, Mitrus I, Smolarczyk R, Cichoń T, Śnietura M, Czaja M, Szala S  (2010): Experimental anticancer therapy with vascular-disruptive peptide and liposome-entrapped chemotherapeutic agent. Arch Immunol Ther Exp. 58: 235-245.

http://www.ncbi.nlm.nih.gov/pubmed/20383751

Szala S, Mitrus I, Sochanik A (2010): Can inhibition of angiogenesis and stimulation of immune response be combined into a more effective antitumor therapy? Cancer Immun Immunother 59: 1449-1455.

http://www.ncbi.nlm.nih.gov/pubmed/20552191

Zawidlak-Wegrzyńska B, Kawalec M, Bosek I, Łuczyk-Juzwa M, Adamus G, Rusin A, Filipczak P, Głowala-Kosińska M, Wolańska K, Krawczyk Z, Kurcok P (2010): Synthesis and antiproliferative properties of ibuprofen-oligo(3-hydroxybutyrate) conjugates. Eur J Med Chem 45: 1833-1842.

http://www.ncbi.nlm.nih.gov/pubmed/20171760

Zięba A, Sochanik A, Szurko A, Rams M, Mrozek A, Cmoch P (2010): Synthesis and in vitro antiproliferative activity of 5-alkyl-12(H)-quino[3,4-b] [1,4]benzothiazinium salts. Eur J Med Chem 45: 4733-4739.

http://www.ncbi.nlm.nih.gov/pubmed/20813435